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New Product for 1-18-10 to 1-24-10 High Throughput DNA Oligos!
Need a plate of high quality oligos fast and for a great price? Allele’s newest product can help…
Introducing High Throughput DNA Oligos!
Anywhere from 48 – 96 desalt oligos per plate
Oligos 20 – 50 bases long
Available in two synthesis scales:
25 nmol scale only 13 cents per base
50 nmol scale only 17 cents per base
Every oligo is strictly controlled for quality:
Oligo quality is verified using MALDI-TOF mass spectrometry or Electrospray Ionization Mass Spectrometry.
Shipped or hand delivered in 5 days!
Oligos can be provided normalized at a specific concentration with fixed or variable volumes. Concentration options depend on the oligo length, purification, and scale of synthesis being ordered.
No minimum number of plates per order required!
To order, simply email your oligo sequences and names, indicate 25 nmol or 50 nmol, concentration preference in excel or notepad format to oligo@allelebiotech.com A template will be posted online here soon, please check back.
Allele…Continuing to introduce cost efficiency to research!
10 Ways to Stay Green in the Lab in 2010
It is hard to do in this business. Numerous consumables, single-use everything to maintain experiment integrity, and constantly ordering reagents with all that packaging! It is a never ending stream of materials that go into experiments dealing with such small molecules. Hope is not lost- there are a few cheap and easy things we as bench scientists can do to help make our labs a little greener.
1 Always recycle- It is mandatory now for most companies and organizations to recycle (especially in California) if they produce more than 1 dumpster full of trash per week. You can do your part in the lab by always putting non-toxic/hazardous recyclables in the recycle bin! Even here in the Allele labs I often find Kimwipe boxes, glove boxes, and even plastic drinking water bottles in the trash and have to fish them out. Always recycling is an easy and, best of all, free thing to do to make your labs more earth friendly.
2 There’s no place like the correct waste receptacle- Every type of waste has its place. Be nice to the earth by putting biohazard in the biohazard, sharps in the sharps, organic solvent waste in the organic solvent waste drum etc.
3 Shut it down!- Always turn off your computer and unused equipment. You can save about $250 per computer per year just by shutting it down every night. Turning off other equipment like the UVP is easy to forget too. Just powering off that at night saves energy and extends the life of the bulb which also saves your lab some cash.
4 Look for ethidium bromide alternatives- This is a work in progress. With all the controversies regarding SYBR and DAPI in their function and mutagenic qualities it seems that there is a call for development of a legitimately safe method to visualize DNA and RNA. Allele is on the case and hopes to have something in the pipeline soon!
5 Swap your boxes- Styrofoam is a necessary evil in the lab. It is the easiest way to transport your temperature sensitive reagents and diagnostics; it is lightweight so it does not add too much to your shipping charges. The bad news is (until better recycling is implemented) that one styrofoam box will be here forever! If you have no occasion to reuse your styrofoam within your own institution there is good news. There are companies out there who will buy your used styrofoam boxes, like Allele with its Box Swap Program, so at the very least that styrofoam box can be used a few more times, eliminating the need to buy it brand new and decreasing demand for this material. If you cannot take advantage of our program then set one up for your own company!
6 Only use dry ice when you have to- If your shipment only requires -20 degrees C for a single day transit time blue ice will work! I have seen it more than I can say when we get a robust reagent sent to us in dry ice with priority shipping. Within the US, priority shipping usually means a transit time about 20 hrs. This last time I saw a small vial in the box which had ~7 lbs of dry ice. This much dry ice will keep a 2lb object frozen for about 24 hrs and someone used it to ship a 10g vial that only needed to be stored at -20 deg C for about 20 hrs! If they had used a 12oz blue ice pack they would have saved on shipping and packaging and we would have been able to reuse the pack, furthering our green endeavors.
7 Close the sash!- This is another great and inexpensive way to save the environment and some money. Closing the hood sash, incubator doors, and refrigerators adds up; constantly leaving them open add up too!
8 Back that thing up!- Since we are lab folk we do not have as many crazy office chain emails going around but I checked and yesterday I sent out 17 emails and received a few more than that! Days like that I shudder to think that there are people out there who receive more than I do on a daily basis and print out every single one for their “records”. This is madness. Please remember to not print emails unless you really need a hard copy. It’s just as easy to save it in a computer file and back your file up.
9 Talk about it- Those motivational types tell you to talk about your goals to others as a means of supporting and motivating yourself to accomplish said goals. Talk to your lab mates and ask them things they can think of to green up your lab. Do not feel weird about seeming “nerdy” by supporting the environment. Chances are, if you work in a lab everyone thinks you are a big nerd already!
10 Network green- I do not like business cards. They are usually made of paper, come in obscene quantities, and do not get recycled. If your title changes or you switch companies you have to go a buy thousands more to update your info. Additionally, they are only for work; there is no social aspect to them and they are too small to really put all your contact info on. Good news is you can go green in networking with Pokens! Pokens are these amazing little animal and people shaped devices that store all your contact info including your company’s website, your email, your social networking pages (i.e. facebook, linkedin, etc.), phone numbers, and whatever else you want. When someone else has a Poken you can “high-four” them and your contact info is swapped. Your Poken can hold many profiles and when it gets full you can load them onto your address book on your computer. There is an upgraded model specifically for business that is not animal shaped and is a zip drive as well. They are relatively new to America and I am one of the many campaigning for them to revolutionize the business card industry! I have two- one for work and one for play.
10 Years of Allele Biotech
Facts about Allele’s 10 years in business:
Products
New product lines added in 2009: iPS cells, Camelid Antibodies, DNA synthesis chemicals, Recombinant Proteins
Highlights: HiTiter Lentiviral Systems, Baculovirus for Mammalian Expression (BacMam), Feeder Cells, shRNA on Viral Vectors, shRNA Validation FP Vector, ProperFold Protein Folding Vector, Validated AllHPLC synthetic siRNA
New Service Groups in 2009: Viral Packaging, RNAi Validation/Screening, FP-based Assay Development
Numbers
Since April, we have added at least one new product every week! We currently run one new promotion per week as well.
A bit of history–did you know that…
Allele Biotech obtained 5 NIH grants in its first three years since establishment. As a matter of fact, Allele Biotech was funded entirely by NIH grants
Allele filed its first patent application in its second year of operation, which was on DNA-driven RNAi and resulted in an outlicensing deal with Promega. As result of the applications, Allele has received 3 US patents on DNA-encoded shRNA, siRNA using promoters such as U6 and H1.
During the past 10 years, Allele was the first to sell U6-based RNAi vectors, the only supplier of bFGF-expressing feeder cells for iPSC, most likely a top 3 provider of baculovirus expression systems, camelid antibody products, iPS creating viral particles, and the most active commercial developer of fluorescent proteins.
Allele Biotech is 10 Years Old and Celebrating with FREE Oligos!
Allele Biotech is 10 years old!!!!!!! December 1999 was when Dr. Jiwu Wang and colleagues started this great company as a DNA oligo and siRNA service provider to the San Diego area. Since then he has fearlessly lead Allele into the forefront of the biotechnology industry with multiple RNAi patents, numerous NIH grants, revolutionary iPSC and fluorescent protein technologies, the acquisition of Orbigen, a continuously growing catalog of over 1000 molecular biology products and signature Allele Biotech Reagents, and a business culture that is approachable, encouraging, and reverential of research advancement through global communication and collaboration.
What a difference a decade makes. Today Allele Biotech is a top oligo service provider all around the country with customers in all of America’s major academic institutions. Currently, we are the sole oligo provider on the University of California San Diego’s central purchasing site, Marketplace; a collaboration designed to provide top quality oligonucleotides to UCSD research departments while saving them thousands of dollars annually. We now produce many of our own oligo synthesis and modification reagents, further cutting the costs to our valuable customers which enabled us to continue operations this last year without raising prices due to the worldwide acetonitrile shortage which more than quadrupled in cost! Allele Biotech has stood out over the years not only to our loyal customers but other oligo providers as well. Less than 5 years into our operation we were approached by one of the well known, top three, oligo providers in an attempt to buy us out! We resisted and are still here to proudly serve the research community with the Allele brand!
It all started with oligos…Now ten years later we want to honor our accomplishment by giving away a FREE month of oligos to one lucky customer! To enter you must be an Allele Biotech Facebook fan or friend. A winner will be randomly selected from our friends/fan pool on Sunday, February 14th, 1210 at noon. That lucky winner will receive FREE oligos for the month of March 2010! Limitations apply. Click here for terms and conditions.
Go Green – Send a free Christmas ePharmaCard!
Go green! Send a free Christmas ePharmaCard to your friends, family, colleagues and clients. ePharmaExpo.com’s new offering ePharmaCards are fun and unique eCards with life science and pharma themes. There is no charge to send these funny eCards. It’s a good way to touch someone’s heart for the holidays while being friendly to the environment.
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